Regenerative Microneedling (exosomes)

The next level of biostimulating skin rejuvenation. Exosomes – tiny messengers of cell communication – deliver precise regeneration and rebuilding signals to the skin. Combined with high-precision microneedling, this creates one of the most modern treatments for stimulating collagen, elastin and skin quality at cellular level.

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Vienna 1180 · Währing Vienna 1060 · Mariahilf

How does exosome needling work?

Exosomes are nanoscale extracellular vesicles – tiny biological messengers of 30 to 150 nanometers that occur in almost all cells and regulate communication between cells. They carry growth factors, peptides, microRNA and other bioactive signaling molecules, thereby controlling repair, regeneration and rebuilding processes in the tissue.

In aesthetic medicine, highly purified exosomes are used that are obtained in specialized laboratories and specifically optimized for skin regeneration. In exosome needling, we combine a high-precision microneedling procedure with the infusion of these active ingredients: through ultra-fine micro-channels, the exosomes reach the upper and middle dermis – right where they take effect.

The effects: activation of the fibroblasts, increased production of collagen and elastin, improved microcirculation and a significantly reduced level of inflammation in the skin. As a result, the skin looks visibly firmer, more even and more radiant – with a skin quality that goes beyond classic active-ingredient treatments. Exosomes are therefore considered the next generation of biostimulating procedures after polynucleotides and PRP.

At a glance

Technique

Microneedling + infusion of exosomes (cellular messengers)

Duration

approx. 60 minutes + 30 minutes anesthetic cream

Cost

from 360 euros (see table)

Downtime

0–2 days (slight redness possible)

Pain

1–3 (scale 1–10)

Result

Best result after 3–4 treatments, visible from 2–4 weeks

What you can expect from exosome needling

Exosomes work on a level that classic active ingredients cannot reach: they speak to the cells in their own language. Instead of addressing individual symptoms, they activate the skin’s entire repair and rebuilding cascade – deeply, broadly and sustainably.

What the treatment achieves:

Cell communication in the body’s own language: Exosomes deliver exactly the signals the skin cells need for regeneration and rebuilding – without introducing foreign volumizing substances into the skin.
Visibly better skin quality: Firmness, elasticity, glow and skin texture improve at the same time – a clearly visible healthy-skin effect instead of isolated wrinkle correction.
Strong collagen and elastin production: The growth factors contained in the exosomes stimulate fibroblasts particularly effectively – with clear effects on firmness and fine lines.
Anti-inflammatory effect: Exosomes modulate inflammatory processes in the skin. They are therefore ideal for a tendency to rosacea, irritated skin or as a follow-up treatment after intensive procedures.
Faster skin regeneration: Ideal in combination with laser, radiofrequency or fractional treatments – healing is faster, and the final result is visibly better.
Improvement of acne scars and pigmentation disorders: The regenerative signals smooth the skin texture and even out the skin tone – a clear advantage for post-acne and fine scars.
Natural result without volume: No change to your facial expressions, no “filled” look – the skin simply looks healthier, smoother and more vital.
Very good tolerability: Since exosomes correspond to the body’s own signaling pathways, the treatment is usually very well tolerated even by sensitive skin.

Exosome needling is particularly suitable

for declining firmness, first fine lines and tired skin
for dull, stressed or easily irritated skin
for a tendency to rosacea or reddened, irritated skin
for acne scars, fine scars or uneven skin texture
as a regenerative follow-up treatment after laser, CO2 or radiofrequency procedures
for patients looking for a highly modern anti-aging treatment without fillers
as preparation for special occasions, for an intense glow effect

Exosome needling compared with other active-ingredient treatments

In recent years, several generations of biostimulating active ingredients have become established. Put simply, the development can be classified as follows:

Active ingredient	Mode of action	Strengths
Hyaluronic acid / skin booster	Moisture retention in the dermis	Immediate hydration and glow effect
Polynucleotides (salmon DNA)	Biostimulation of the fibroblasts via DNA fragments	Skin quality, elasticity, gentle regeneration
Exosomes	Cell communication via growth factors, peptides and microRNA	Broadest range of effects: regeneration, anti-inflammation, skin structure, glow

Our tip: Polynucleotides and exosomes complement each other excellently. We use exosomes especially where particularly intensive regeneration, an inflammation-modulating effect or a very broad improvement in skin quality is desired.

Costs

Here you can find our complete price list: View price list

B Needling ladder

Three levels: entry level → salmon PDRN → exosomes

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Prices: Needling ladder
No.	Item	Single price	Series / package	Series price
B.1	Classic MicroneedlingMicroneedling with hyaluronic serum – the first step on the ladder	200 €	Series of 3 (–10 %)	540 €
B.2	Repair Microneedling (PDRN)Supports the regeneration of damaged skin and provides intensive hydration	230 €	Series of 3 (–10 %)	621 €
B.3	Regenerative Microneedling (exosomes)Innovative skin rejuvenation with regenerative exosome technology	360 €	Series of 3 (–10 %)	972 €

See the full price list

Online Appointment

Exosome needling can be booked individually or as part of an individual treatment plan – for example combined with radiofrequency needling, medical peels or as a follow-up treatment after laser procedures. Consultation and treatment are carried out by our experienced team at the institute for medical cosmetics.

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FAQs

Frequently asked questions about exosome needling

What exactly are exosomes?

Exosomes are nanoscale extracellular vesicles – natural packages of messengers used for cell communication. They contain growth factors, peptides, microRNA and other bioactive molecules and thereby transmit signals between cells. In aesthetic medicine, highly purified exosomes specifically optimized for skin regeneration are used.

How does exosome needling differ from the salmon DNA facial?

Both treatments are biostimulating but work on different levels. Polynucleotides (salmon DNA) stimulate the fibroblasts primarily via DNA fragments and lead to better skin quality, elasticity and moisture retention. Exosomes work more broadly – via a large number of signaling molecules – and address regeneration, inflammation modulation and skin structure at the same time. The two procedures complement each other very well.

Are exosomes a filler?

No. Exosomes do not add volume. They are signaling molecules that stimulate the skin to regenerate itself and to form more collagen, elastin and hyaluronic acid. The result is natural and develops over several weeks.

Who is the treatment suitable for?

For almost all skin types – especially for declining firmness, dull or stressed skin, a tendency to rosacea, acne scars and as a regenerative follow-up treatment after more intensive procedures. The procedure is usually very well tolerated even by very sensitive skin.

How often should I have the treatment?

We recommend a course of 3–4 sessions 3–4 weeks apart. To maintain the result, a refresher every 4–6 months is ideal.

What does the skin look like right after the treatment?

Slight redness, small pinpoint bleeding spots or slight swelling may occur briefly. These usually subside within 24 to 48 hours. Make-up is usually possible again the following day.

When is the result visible?

A first glow often appears just a few days after the treatment. The actual biostimulating effect – that is, the formation of new collagen and elastin – develops over several weeks. The best result is visible after the course is complete.

Can exosome needling be combined with other procedures?

Yes, very well in fact. Exosomes combine ideally with radiofrequency needling, fractional radiofrequency, IPL, laser treatments or classic microneedling. Their use as a regenerative follow-up treatment after intensive treatments such as a CO2 laser or picosecond laser has proven particularly effective – healing is faster, and the final result is better.

Is exosome needling also suitable for sensitive skin or rosacea?

Yes. Exosomes have an inflammation-modulating effect and are one of the few treatments that can also be used meaningfully if you have a tendency to rosacea. We clarify your individual suitability in the preliminary consultation.

Are exosomes safe?

We use only highly purified exosome preparations processed in specialized laboratories that meet the applicable quality and safety standards. In the preliminary consultation we clarify your individual suitability and possible contraindications.

When must the treatment not be performed?

The treatment is not performed during pregnancy and breastfeeding, in the case of acute skin inflammation or herpes outbreaks in the treatment area, active autoimmune diseases, active cancer, or a known allergy to the local anesthetic used or to ingredients of the preparation. If you take blood thinners, please consult us beforehand.

Do I need to avoid sunlight after the treatment?

Direct sunlight should be avoided for 1–2 weeks, and sun protection with SPF 50+ is a must during this time – also for an optimal treatment result.

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